Sputnik is not an mRNA vax; it's an adenovirus vax like J&J *
by irishlaw2010 (2021-04-12 11:53:41)
Edited on 2021-04-12 11:56:21

In reply to: My understanding is that the first Russian vax was covid  posted by Pjnuge


"In the past, it has taken years, even decades, to bring new vaccines to market. Attenuated vaccines, such as those for measles, mumps, and rubella, involve weakening a virus to non-dangerous strength; inactivated vaccines, as in most flu shots, render it inert. Developing such vaccines is a tricky process of trial and error. Research into mRNA vaccines—which, in contrast to traditional vaccines, are synthetic, carrying a portion of a virus’s genetic code—began in the nineteen-nineties. Though the mRNA technology was unproved until last year, it was also tantalizingly simple, akin to programming a script of computer software. Moderna, a pharmaceutical company founded in 2010 with a focus on mRNA, created its vaccine prototype during a weekend in January, 2020. In mid-March, the pharmaceutical giant Pfizer, working with the German company BioNTech, came up with twenty contenders for a vaccine; by early April, they had been whittled down to four.

Sputnik V—like several other covid-19 vaccines, developed by Oxford University and AstraZeneca, in the United Kingdom; CanSino Biologics, in China; and Johnson & Johnson, in the United States—is what is known as a vector vaccine. This type of vaccine is much newer than the attenuated or inactivated kind but has a longer track record than the mRNA variety."




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