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In 2013, No. 10 MSU beat No. 2 OSU. by tdiddy07

In 2007, No. 9 OU beat No. 1 Kansas. Although it's possible OU was actually favored.

In 2017, No. 6 UGA beat No. 2 Auburn in a grudge match.

All prevented the losers from playing in the championship game/playoff.

The Big 12 seems to have had upsets more frequently in games that costs teams shots at the title. In 1998, No. 8 A&M beat No. 3 undefeated Kansas State, who would've advanced past UCLA after the Bruins lost to Miami in a Hurricane-rescheduled game that week. In 1996, unranked Texas beat No. 3 Nebraska, who would've gone to the Sugar Bowl to play Florida State because No. 2 Arizona State went to the Rose Bowl, where they lost to Ohio State. In 2001, No. 9 Colorado beat No. 3 Texas, who would've jumped in to the championship after No. 2 Florida lost to Tennessee, who then lost to LSU in the Sugar Bowl.

2011 was almost an upset that could've prevented Kelly from going to ND. No. 22 Nebraska lost by 1 to No. 3 Texas, who eventually went to the Championship Game after 1 second was put back on the clock for a game-ending field goal. A Texas loss could've vaulted UC to No. 2 to play in the title game after No. 2 Florida lost to Alabama and UC jumped over undefeated TCU after beating Pitt to finish 3rd in the BCS standing. Though that's no guarantee. They could've voted differently to avoid a Big East newcomer. Though they wouldn't want a rematch, and TCU inexplicably dropped behind UC even though it's best wins were slightly better than UC's and in much more convincing fashion.