In reply to: Except that we have never had mRNA vaccines before. posted by pjnuge
The RSV mRNA vaccine was a failure and never made it into mass production.I am not concerned with the safety profile of any of these vaccines but would be more concerned with a new process than one in use for decades.
There are some early MRNA TSV trials going on now. Also Novavax uses a nanoparticle delivery system we haven't used before. The adenovirus used in J&J has only been used with Ebola vaccine attempts... not exactly long lasting tech.
They're all safe, but the mRNA new = less safe isn't a great arguement.
There has never been a set of new vaccines administered this much this fast world wide before. In effect we are getting 5-10 years worth of adverse event data quarterly right now compared to a normal drug.
Yes, we don't have long term data -- longer than one year, since some in trials are about a year now. For every other possible reaction across any demographic of any kind we have more data collected than ever before for something new. A lot of drugs with far worse potential side effects - death -- often only are administered to millions of people per year. We are doing 3 million per day in the US alone right now.