Theoretically, if you get the shot today will that last through the fall semester as ND wishes? Or, will ND require a shot closer to August?
Longest approved vaccine = least chance for a rare side effect to pop out of nowhere.
The technology used by Janssen and now Novavax has been around decades, even live attenuated vax is in common use for other diseases. If you were worried about rare side effects I would go Janssen ( JandJ). Or wait for the Novavax.
and years prior to these particular covid-19 vaccines. They also have very, very few ingredients relative to other vaccines (pretty much the only window for bad allergies or anaphylactic shock comes in the form of potential reaction to the lipids involved and those are exceedingly rare), so they're actually far safer in most regards.
The mRNA itself breaks down extremely quickly in the body and it's a very targeted approach in and of itself as well.
These mRNA vaccines are very safe and the testing has already and will continue to bear that out. The only rough part with these vaccines are how they really prime up your immune system to fight off an infection, and those side effects quickly subside.
The RSV mRNA vaccine was a failure and never made it into mass production.I am not concerned with the safety profile of any of these vaccines but would be more concerned with a new process than one in use for decades.
There are some early MRNA TSV trials going on now. Also Novavax uses a nanoparticle delivery system we haven't used before. The adenovirus used in J&J has only been used with Ebola vaccine attempts... not exactly long lasting tech.
They're all safe, but the mRNA new = less safe isn't a great arguement.
There has never been a set of new vaccines administered this much this fast world wide before. In effect we are getting 5-10 years worth of adverse event data quarterly right now compared to a normal drug.
Yes, we don't have long term data -- longer than one year, since some in trials are about a year now. For every other possible reaction across any demographic of any kind we have more data collected than ever before for something new. A lot of drugs with far worse potential side effects - death -- often only are administered to millions of people per year. We are doing 3 million per day in the US alone right now.
grown in a lab, which is on the outside of the virus (which combine with the ACE receptors in your cells to cause infection). The vaccine is very effective in causing a robust immune response but only has tiny fragments of viral protein and no genetic material.
it encodes a stabilized part of the spike protein but it is a viral vector and not mRNA
sequences and not mRNA. Merck has an inactivated viral vaccine that got shelved. The Russians have one, they didn’t do phase 3 testing on but went straight from phase 2 to human use, from what I understand, as do the Chinese.
is allegedly just the stolen Johnson & Johnson vaccine.
viruses altered chemically or irradiated to attenuate them and they skipped the 3rd phase of trials- proof of prevention in humans. They could have stolen J and Js but it takes time to grow and process all those tiny proteins. Much faster to steal an mRNA vaccine recipe, I think. Unless of course you just steal a shipment of vaccine.
"In the past, it has taken years, even decades, to bring new vaccines to market. Attenuated vaccines, such as those for measles, mumps, and rubella, involve weakening a virus to non-dangerous strength; inactivated vaccines, as in most flu shots, render it inert. Developing such vaccines is a tricky process of trial and error. Research into mRNA vaccines—which, in contrast to traditional vaccines, are synthetic, carrying a portion of a virus’s genetic code—began in the nineteen-nineties. Though the mRNA technology was unproved until last year, it was also tantalizingly simple, akin to programming a script of computer software. Moderna, a pharmaceutical company founded in 2010 with a focus on mRNA, created its vaccine prototype during a weekend in January, 2020. In mid-March, the pharmaceutical giant Pfizer, working with the German company BioNTech, came up with twenty contenders for a vaccine; by early April, they had been whittled down to four.
Sputnik V—like several other covid-19 vaccines, developed by Oxford University and AstraZeneca, in the United Kingdom; CanSino Biologics, in China; and Johnson & Johnson, in the United States—is what is known as a vector vaccine. This type of vaccine is much newer than the attenuated or inactivated kind but has a longer track record than the mRNA variety."